The GPRC6A Polyclonal Antibody (CAB8525) is a valuable tool for researchers studying GPRC6A, a G protein-coupled receptor potentially involved in various physiological processes such as glucose and lipid metabolism, as well as bone mineralization. This antibody, produced in rabbits, demonstrates high specificity for human samples and has been validated for use in Western blotting applications.GPRC6A is gaining attention for its potential role in metabolic disorders, including diabetes and obesity, as well as in bone health. By targeting this receptor, researchers can better understand its signaling pathways and potential therapeutic implications in these disease states.
The GPRC6A Polyclonal Antibody allows for the detection and analysis of GPRC6A expression in different cell types, making it a versatile tool for studies in both metabolic and bone research.Overall, the GPRC6A Polyclonal Antibody is a valuable resource for scientists interested in unraveling the complex functions of GPRC6A and exploring its potential as a therapeutic target in metabolic and skeletal disorders.
Product Name:
GPRC6A Rabbit Polyclonal Antibody
SKU:
CAB8525
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-590 of human GPRC6A (NP_683766.2).
Members of family C of the G protein-coupled receptor (GPCR) superfamily, such as GPRC6A, are characterized by an evolutionarily conserved amino acid-sensing motif linked to an intramembranous 7-transmembrane loop region. Several members of GPCR family C, including GPRC6A, also have a long N-terminal domain (summary by Pi et al., 2005 [PubMed 16199532]).
Purification Method:
Affinity purification
Gene ID:
222545
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GPRC6A antibody (CAB8525) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
