The GPRC5C Polyclonal Antibody (PAC004744) is a valuable tool for researchers studying GPRC5C, a G protein-coupled receptor protein involved in various cellular processes. This antibody, produced in rabbits, is highly specific to human samples and is ideal for use in Western blot experiments.GPRC5C is known to play a role in cell proliferation, differentiation, and potentially tumorigenesis, making it a target of interest in cancer research. By binding to the GPRC5C protein, this antibody allows for the detection and analysis of GPRC5C expression in different cell types, providing insights into its function and potential therapeutic applications.
The exploration of GPRC5C and its signaling pathways has the potential to uncover new targets for drug development and personalized medicine in the treatment of various diseases, including cancer. With its high reactivity and specificity, the GPRC5C Polyclonal Antibody is a valuable tool for advancing research in the fields of molecular biology and oncology.
Antibody Name:
GPRC5C Antibody
Antibody SKU:
PACO04744
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human, Mouse, Rat, Monkey
Immunogen:
synthesized peptide derived from the Internal region of human GPRC5C.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
GPRC5C; RAIG3; PSEC0087; G-protein coupled receptor family C group 5 member C; Retinoic acid-induced gene 3 protein; RAIG-3
UniProt Protein Function:
GPRC5C: This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Belongs to the G-protein coupled receptor 3 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 3Chromosomal Location of Human Ortholog: 17q25Cellular Component: cytoplasmic vesicle membrane; mitochondrion; integral to plasma membrane; receptor complex; vesicleMolecular Function: G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
G-protein coupled receptor family C group 5 member C isoform b
NCBI Synonym Full Names:
G protein-coupled receptor, class C, group 5, member C
NCBI Official Symbol:
GPRC5CÂ Â
NCBI Official Synonym Symbols:
RAIG3; RAIG-3Â Â
NCBI Protein Information:
G-protein coupled receptor family C group 5 member C; orphan G-protein coupled receptor; retinoic acid-induced gene 3 protein; retinoic acid responsive gene protein; G protein-coupled receptor, family C, group 5, member C
UniProt Protein Name:
G-protein coupled receptor family C group 5 member C