The GPRC5A Polyclonal Antibody (CAB8173) is a crucial tool for researchers studying GPRC5A, a G protein-coupled receptor family member involved in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the GPRC5A protein, this antibody enables precise detection and analysis in a range of cell types, making it particularly suitable for investigations in the fields of cell biology and signal transduction.
GPRC5A, also known as retinoic acid-induced protein 3 (RAI3), is implicated in multiple physiological functions such as cell growth, cell differentiation, and immune response regulation. Its role in cancer development and progression has also been studied extensively, with potential implications for targeted therapies in oncology. By gaining insights into the function and regulation of GPRC5A, researchers may uncover new strategies for treating cancer and other diseases related to abnormal cell signaling pathways.
Product Name:
GPRC5A Rabbit Polyclonal Antibody
SKU:
CAB8173
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 268-357 of human GPRC5A (NP_003970.1).
This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation.
Purification Method:
Affinity purification
Gene ID:
9052
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of MKN-45, using GPRC5A Rabbit pAb (CAB8173) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
