The GPR83 Polyclonal Antibody (PAC040682) is a valuable tool for research involving GPR83, a G protein-coupled receptor that plays a key role in various physiological processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications. By binding to the GPR83 protein, researchers can accurately detect and analyze its expression in different cell types, providing crucial insights into its function and potential implications in various research areas such as neurobiology and metabolism.
GPR83 is known to be involved in the regulation of appetite, energy balance, and immune responses, making it a promising target for studies related to obesity, metabolic disorders, and immune system modulation. By understanding the mechanisms underlying GPR83 activity, researchers can uncover novel therapeutic strategies for addressing these conditions and potentially developing targeted treatments that aim to modulate GPR83 function. The GPR83 Polyclonal Antibody provides researchers with a reliable tool to advance their investigations into the role of GPR83 in health and disease.
Western blot. All lanes: GPR83 antibody at 2µg/ml. Lane 1: HCT116 whole cell lysate. Lane 2: U87 whole cell lysate. Lane 3: MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 49 kDa. Observed band size: 49 kDa.
Immunofluorescent analysis of Hela cells using PACO40682 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Orphan receptor. Could be a neuropeptide Y receptor.
GPR83: Orphan receptor. Could be a neuropeptide Y receptor. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1Chromosomal Location of Human Ortholog: 11q21Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: G-protein coupled receptor activityBiological Process: cell surface receptor linked signal transduction
