The GPR68 Polyclonal Antibody (CAB7348) is a valuable tool for researchers studying GPR68, a G-protein coupled receptor involved in various physiological processes such as pH sensing and signaling. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the GPR68 protein, researchers can accurately detect and analyze its expression in different cell types, making it an ideal choice for investigations in areas such as neuroscience and cancer research.
GPR68, also known as ovarian cancer G-protein coupled receptor 1 (OGR1), plays a crucial role in regulating pH levels in the body and is associated with conditions such as cancer and neurological disorders. Understanding the function and mechanisms of GPR68 is essential for developing novel therapeutic strategies targeting this receptor for the treatment of various diseases. With its specificity and sensitivity, the GPR68 Polyclonal Antibody (CAB7348) is a valuable tool for elucidating the role of GPR68 in health and disease.
Product Name:
GPR68 Rabbit Polyclonal Antibody
SKU:
CAB7348
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 276-365 of human GPR68 (NP_003476.3).
The protein encoded by this gene is a G protein-coupled receptor for sphingosylphosphorylcholine. The encoded protein is a proton-sensing receptor, inactive at pH 7.8 but active at pH 6.8. Mutations in this gene are a cause of amelogenesis imperfecta.
Purification Method:
Affinity purification
Gene ID:
8111
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts from normal (control) and GPR68 knockout (KO) 293T cells, using GPR68 antibody (CAB7348) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
