The GPR62 Polyclonal Antibody (CAB16163) is a versatile tool for researchers studying GPR62, a G protein-coupled receptor that plays a role in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GPR62 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in neuroscience, metabolism, and cancer biology.
GPR62 is known to be involved in regulating neural development, synaptic plasticity, and energy metabolism, making it a promising target for research on neurological disorders, metabolic diseases, and cancer progression. Understanding the functions and interactions of GPR62 is crucial for uncovering its implications in these areas and potentially developing targeted therapies in the future.
Product Name:
GPR62 Rabbit Polyclonal Antibody
SKU:
CAB16163
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human GPR62 (NP_543141.3).
Sequence:
GTPP APPP APAR CSVL AGGL GPFR PLWA LLAF ALPA LLLL GAYG GIFV VARR AALR PPRP ARGS RLHS DSLD SRLS ILPP LRPR LPGG KAAL APAL AVGQ F
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
GPCR8; KPG_005; GPR62
Positive Sample:
SH-SY5Y
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, Multi-pass membrane protein
Calculated MW:
38kDa
Observed MW:
39kDa
Enables arrestin family protein binding activity. Involved in G protein-coupled receptor signaling pathway; inositol phosphate-mediated signaling; and positive regulation of cAMP-mediated signaling. Located in endosome and plasma membrane. Part of receptor complex.
Purification Method:
Affinity purification
Gene ID:
118442
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from SH-SY5Y cells, using GPR62 Rabbit pAb (CAB16163) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
