The GPR6 Polyclonal Antibody (CAB14738) is a valuable tool for researchers investigating GPR6, a G protein-coupled receptor involved in neurological disorders and immune system regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the GPR6 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in neuroscience and immunology research.GPR6 is known for its role in modulating neurotransmitter release and synaptic transmission, making it a potential target for therapeutic interventions in conditions such as Parkinson's disease and drug addiction.
Additionally, GPR6 has been linked to immune system regulation, suggesting its involvement in inflammatory processes and autoimmune disorders. Investigating the function of GPR6 is essential for understanding its impact on neurological and immune-related diseases, paving the way for novel therapeutic strategies in the future.
Product Name:
GPR6 Rabbit Polyclonal Antibody
SKU:
CAB14738
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 253-362 of human GPR6 (NP_005275.1).
Predicted to enable sphingosine-1-phosphate receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within positive regulation of cytosolic calcium ion concentration. Predicted to be integral component of plasma membrane. Predicted to be active in cytoplasm and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
2830
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-251MG cells, using GPR6 Rabbit pAb (CAB14738) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
