The GPR45 Polyclonal Antibody (CAB15790) is a valuable tool for researchers studying GPR45, a G protein-coupled receptor involved in various biological processes. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the GPR45 protein, this antibody allows for the detection and analysis of GPR45 in different cell types, making it an essential component for studies in pharmacology and drug development.GPR45, also known as an orphan G protein-coupled receptor, is a promising target for drug discovery and development due to its potential role in regulating various physiological functions.
Research on GPR45 has implications in fields such as neuroscience, metabolism, and inflammation, making it a versatile tool for investigating the mechanisms underlying various diseases. Understanding the function of GPR45 is essential for the development of novel therapeutics targeting this receptor in the treatment of various disorders.
Product Name:
GPR45 Rabbit Polyclonal Antibody
SKU:
CAB15790
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human GPR45 (NP_009158.3).
This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system.
Purification Method:
Affinity purification
Gene ID:
11250
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from SH-SY5Y cells, using GPR45 Rabbit pAb (CAB15790) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
