The GPR42 Polyclonal Antibody (PAC003955) is a valuable tool for research involving GPR42, a G protein-coupled receptor implicated in various biological processes, including immune response modulation and metabolic regulation. This antibody, developed using rabbit immunization, exhibits high reactivity with human samples and has been validated for use in Western blot applications.GPR42, also known as G-protein coupled receptor 42, plays a crucial role in mediating signals in response to certain ligands, thereby modulating immune responses and metabolic functions. Its involvement in these pathways makes it a promising target for research into diseases like obesity, diabetes, and inflammatory conditions.
By detecting and analyzing GPR42 protein expression in different cell types, this antibody enables researchers to gain insights into the mechanisms underlying these diseases and develop potential therapeutic strategies.Overall, the GPR42 Polyclonal Antibody is a valuable tool for studying the functions and regulation of GPR42 in various physiological and pathological contexts, providing valuable insights into its potential role as a therapeutic target in metabolic and immune-related disorders.
Antibody Name:
GPR42 Antibody
Antibody SKU:
PACO03955
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the N-terminal region of human GPR42.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
GPR42; GPR42P; G-protein coupled receptor 42
UniProt Protein Function:
GPR42: May act as a receptor for short chain fatty acids, such as propionate. Belongs to the G-protein coupled receptor 1 family.Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 19q13.1Cellular Component: integral to plasma membraneMolecular Function: G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway