The GPR4 Polyclonal Antibody (CAB15998) is specifically designed for research involving GPR4, a G protein-coupled receptor that plays a role in various physiological processes, including immune response and inflammation regulation. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the GPR4 protein, it allows for detection and analysis in a variety of cell types, making it suitable for studies in immunology and inflammatory diseases research.
GPR4, also known as proton-sensing G protein-coupled receptor, is involved in pH sensing and cellular responses to acidic environments. Its role in immune modulation and inflammation regulation makes it a promising target for research into diseases such as cancer, cardiovascular diseases, and inflammatory disorders. Understanding the function of GPR4 is essential for developing therapeutic strategies that target its signaling pathways to potentially treat or manage these conditions.
Product Name:
GPR4 Rabbit Polyclonal Antibody
SKU:
CAB15998
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 283-362 of human GPR4 (NP_005273.1).
Enables G protein-coupled receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; positive regulation of Rho protein signal transduction; and response to acidic pH. Located in plasma membrane.
Purification Method:
Affinity purification
Gene ID:
2828
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GPR4 Rabbit pAb (CAB15998) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
