The GPR37 Polyclonal Antibody (CAB16724) is a valuable tool for researchers studying GPR37, a G-protein coupled receptor that plays a key role in various biological processes. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blot applications. It targets the GPR37 protein, enabling precise detection and analysis in a range of cell types, making it an excellent choice for studies in neuroscience and drug discovery.GPR37, also known as parkin-associated endothelin receptor-like receptor (Pael-R), is involved in regulating dopamine neurotransmission and is implicated in neurodegenerative disorders such as Parkinson's disease.
Its importance in controlling neuronal function makes it a promising target for research into neurological conditions and potential therapeutic interventions. Investigating the function of GPR37 is crucial for gaining insights into its role in health and disease, paving the way for the development of novel treatment strategies.
Product Name:
GPR37 Rabbit Polyclonal Antibody
SKU:
CAB16724
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-180 of human GPR37 (NP_005293.1).
This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease.
Purification Method:
Affinity purification
Gene ID:
2861
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GPR37 Rabbit pAb (CAB16724) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
