Anti-GPR22 Antibody (CAB18313)
- SKU:
- CAB18313
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Anti-GPR22 Antibody (CAB18313)
The GPR22 Rabbit Polyclonal Antibody (CAB18313) is a powerful tool for researchers studying GPR22, a G-protein coupled receptor involved in various physiological processes. This antibody, raised in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the GPR22 protein, this antibody enables accurate detection and analysis in multiple cell types, making it ideal for investigations in pharmacology and neurobiology.GPR22, also recognized as an orphan GPCR, plays a vital role in modulating cell signaling pathways and neurotransmitter release, making it a promising target for drug development in neurological disorders and psychiatric conditions.
Its involvement in regulating neuronal functions suggests its potential as a therapeutic target for diseases like Alzheimer's, Parkinson's, and mood disorders. Deepening our understanding of GPR22 function is essential for advancing drug discovery efforts aimed at treating these challenging conditions.
| Antibody Name: | Anti-GPR22 Antibody |
| Antibody SKU: | CAB18313 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human GPR22. |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, U-251MG, SH-SY5Y, HepG2, Mouse heart, Mouse brain, Rat heart, Rat brain |
| Immunogen: | Recombinant protein of human GPR22. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2845 |
| Uniprot: | Q99680 |
| Cellular Location: | |
| Calculated MW: | 49kDa |
| Observed MW: | 55kDa |
 | Western blot - GPR22 Polyclonal Antibody (CAB18313) |
| Synonyms: | GPR22 |
| Background: | This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein. |
| UniProt Protein Function: | GPR22: Orphan receptor. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR Chromosomal Location of Human Ortholog: 7q22-q31.1 Cellular Component: integral to plasma membrane Molecular Function:peptide binding Biological Process: cellular response to hormone stimulus |
| NCBI Summary: | This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99680 |
| NCBI GenInfo Identifier: | 116242502 |
| NCBI Gene ID: | 2845 |
| NCBI Accession: | Q99680.2 |
| UniProt Secondary Accession: | Q99680,O14554, |
| UniProt Related Accession: | Q99680 |
| Molecular Weight: | 49,265 Da |
| NCBI Full Name: | Probable G-protein coupled receptor 22 |
| NCBI Synonym Full Names: | G protein-coupled receptor 22 |
| NCBI Official Symbol: | GPR22Â Â |
| NCBI Protein Information: | probable G-protein coupled receptor 22 |
| UniProt Protein Name: | Probable G-protein coupled receptor 22 |
| Protein Family: | Probable G-protein coupled receptor |
| UniProt Gene Name: | GPR22Â Â |
| UniProt Entry Name: | GPR22_HUMAN |
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