The GPR180 Polyclonal Antibody (PAC04922) is a valuable tool for researchers studying GPR180, a G protein-coupled receptor involved in various cellular processes. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding to the GPR180 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in the fields of cell biology and signal transduction.GPR180 plays a pivotal role in mediating intracellular signaling pathways and is implicated in the regulation of diverse biological functions.
Its involvement in cellular responses to extracellular stimuli makes it a key target for research into areas such as metabolism, cell proliferation, and hormone regulation. Understanding the functions of GPR180 is essential for unraveling its potential implications in disease pathogenesis and for developing targeted therapies in conditions such as metabolic disorders and hormone-related diseases.
Antibody Name:
GPR180 Antibody (PACO49222)
Antibody SKU:
PACO49222
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Integral membrane protein GPR180 protein (114-168AA)
Immunofluorescent analysis of HepG2 cells using PACO49222 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
extracellular exosome
Synonyms:
Integral membrane protein GPR180 (Intimal thickness-related receptor), GPR180, ITR
UniProt Protein Function:
GPR180: Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 13q32.1Cellular Component: integral to membraneBiological Process: G-protein coupled receptor protein signaling pathway; response to pheromone
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that is a member of the G protein-coupled receptor superfamily. This protein is produced predominantly in vascular smooth muscle cells and may play an important role in the regulation of vascular remodeling. [provided by RefSeq, Jul 2008]
