The GPR174 Polyclonal Antibody (PACO05529) is a valuable tool for researchers studying GPR174, a G protein-coupled receptor involved in immune regulation and inflammation modulation. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding to the GPR174 protein, this antibody allows for precise detection and analysis in various cell types, making it an essential component for studies in immunology and inflammatory disease research.GPR174, also known as a putative chemokine receptor, is implicated in the regulation of immune responses and has been linked to various inflammatory conditions and autoimmune disorders.
Its role in immune cell activation and chemotaxis makes it a promising target for therapeutic interventions aimed at modulating immune function in disease settings. By investigating the function of GPR174, researchers can uncover new insights into immune regulation and potentially develop novel treatment strategies for inflammatory diseases and immune-related disorders.
Antibody Name:
GPR174 Antibody (PACO05529)
Antibody SKU:
PACO05529
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from the Internal region of human GPR174.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
GPR174: Putative receptor for purines coupled to G-proteins. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCRChromosomal Location of Human Ortholog: Xq21.1
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein belonging to the G protein-coupled receptor superfamily. These proteins are characterized by the presence of seven alpha-helical transmembrane domains, and they activate or interact with various endogenous or exogenous ligands, including neurotransmitters, hormones, and odorant and taste substances. This family member is classified as an orphan receptor because the cognate ligand has not been identified. [provided by RefSeq, Sep 2011]
