The GPR161 Polyclonal Antibody (PACO09562) is a vital tool for researchers studying G protein-coupled receptor 161 (GPR161), which plays a key role in various cellular processes including signaling pathways and development. This antibody is produced in rabbits and has been shown to have high reactivity with human samples, making it ideal for use in Western blot applications.GPR161 is a receptor protein involved in regulating various physiological functions such as cell proliferation, differentiation, and migration. Dysregulation of GPR161 has been linked to diseases like cancer, neurological disorders, and developmental abnormalities.
By using the GPR161 Polyclonal Antibody, researchers can detect and analyze the expression of GPR161 in different cell types, enabling them to further understand its role in health and disease.Overall, this antibody is a valuable tool for scientists and researchers looking to investigate the functions and mechanisms of GPR161, paving the way for potential therapeutic interventions in various disease conditions.
G protein-coupled receptor 161;GPR161;FLJ33952;RE2 ;
UniProt Protein Function:
GPR161: Orphan receptor. Plays a role in neurulation and lens development. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCRChromosomal Location of Human Ortholog: 1q24.2Cellular Component: cilium; recycling endosomeMolecular Function: G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; positive regulation of cAMP biosynthetic process
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017]
