The GPR15 Polyclonal Antibody (PAC020641) is a vital tool for researchers studying G protein-coupled receptor 15 (GPR15), a protein involved in immune cell recruitment and inflammatory responses. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for use in Western blot applications. By binding to GPR15, this antibody enables the detection and analysis of this important protein in various cell types, allowing for valuable insights into immunology and inflammatory processes.
GPR15 is known for its role in mediating the homing of immune cells to the gut and promoting inflammation in response to infection or injury. Its involvement in immune cell trafficking and inflammatory signaling pathways makes it a key target for research in areas such as gastrointestinal diseases, inflammatory disorders, and immune responses to microbial pathogens. By elucidating the function of GPR15, researchers can uncover potential therapeutic strategies for modulating immune cell behavior and combatting inflammatory conditions.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20641(GPR15 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 8%SDS-PAGE,Lysate: 40 µg,Lane 1-4: HepG2 cells, 231 cells, Hela cells, Lovo cells,Primary antibody: PACO20641(GPR15 Antibody) at dilution 1/350 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 20 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20641(GPR15 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane.
Synonyms:
G protein-coupled receptor 15
UniProt Protein Function:
GPR15: Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCRChromosomal Location of Human Ortholog: 3q11.2-q13.1Cellular Component: integral to plasma membrane; plasma membrane
UniProt Protein Details:
NCBI Summary:
This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012]
