GPR143 Rabbit Polyclonal Antibody (CAB10568)
- SKU:
- CAB10568
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GPR143 Rabbit Polyclonal Antibody |
SKU: | CAB10568 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 314-404 of human GPR143 (NP_000264.2). |
Sequence: | TGCS LGFQ SPRK EIQW ESLT TSAA EGAH PSPL MPHE NPAS GKVS QVGG QTSD EALS MLSE GSDA STIE IHTA SESC NKNE GDPA LPTH GDL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | OA1; NYS6; GPR143 |
Positive Sample: | U-251MG,BT-474,SW480,Mouse liver,Mouse kidney,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Apical cell membrane, Golgi apparatus, Lysosome membrane, Melanosome membrane, Multi-pass membrane protein. |
Calculated MW: | 44kDa |
Observed MW: | 44kDa |
This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.
Purification Method: | Affinity purification |
Gene ID: | 4935 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |