The GPR123 Polyclonal Antibody (PACO05521) is a vital tool for research involving GPR123, a G protein-coupled receptor known for its role in various physiological processes. This antibody, created using rabbits, exhibits high reactivity with human samples and is validated for use in applications such as Western blot analysis. By binding specifically to the GPR123 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent choice for studies in neuroscience and drug development.
GPR123, also called the orphan adhesion-like GPCR, is involved in functions related to the central nervous system and has been linked to neurological disorders and mental health conditions. Its importance in regulating pathways related to neuronal growth and plasticity makes it a target of interest for research into conditions like schizophrenia, mood disorders, and neurodegenerative diseases. Understanding the role of GPR123 is crucial for developing potential treatments that target this receptor and its associated pathways.
Antibody Name:
GPR123 Antibody (PACO05521)
Antibody SKU:
PACO05521
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:5000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the C-terminal region of human GPR123.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
This gene encodes a protein that belongs to the adhesion family of G-protein-coupled receptors. Members of this family function in several sensory systems and regulate blood pressure, immune responses, food intake and development. A similar protein in rodents is thought to play a role in in the regulation of neuronal signaling pathways. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Mar 2014]
