GPNMB Rabbit Polyclonal Antibody (CAB14270)
- SKU:
- CAB14270
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GPNMB Rabbit Polyclonal Antibody |
SKU: | CAB14270 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-486 of human GPNMB (NP_001005340.1). |
Sequence: | KRFH DVLG NERP SAYM REHN QLNG WSSD ENDW NEKL YPVW KRGD MRWK NSWK GGRV QAVL TSDS PALV GSNI TFAV NLIF PRCQ KEDA NGNI VYEK NCRN EAGL SADP YVYN WTAW SEDS DGEN GTGQ SHHN VFPD GKPF PHHP GWRR WNFI YVFH TLGQ YFQK LGRC SVRV SVNT ANVT LGPQ LMEV TVYR RHGR AYVP IAQV KDVY VVTD QIPV FVTM FQKN DRNS SDET FLKD LPIM FDVL IHDP SHFL NYST INYK WSFG DNTG LFVS TNHT VNHT YVLN GTFS LNLT VKAA APGP CPPP PPPP RPSK PTPS LATT LKSY DSNT PGPA GDNP LELS RIPD ENCQ INRY GHFQ ATIT IVEG ILEV NIIQ MTDV LMPV PWPE SSLI DFVV TCQG SIPT EVCT IISD PTCE ITQN TVCS PVDV DEMC LLTV RRTF NGSG TYCV NLTL GDDT SLAL TSTL ISVP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | NMB; HGFIN; PLCA3; GPNMB |
Positive Sample: | SK-MEL-28,Rat eye |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Melanosome, Single-pass type I membrane protein. |
Calculated MW: | 64kDa |
Observed MW: | 64kDa/90-120kDa |
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10457 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |