GPD1L Monoclonal Antibody [PAT14E2AT] (CPAB0236)
- SKU:
- CPAB0236
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT14E2AT
- Applications:
- WB
- ELISA
- FC
Description
GPD1L Monoclonal Antibody [PAT14E2AT] (CPAB0236)
The GPD1L Polyclonal Antibody (CPAB0236) is a vital tool for researchers studying GPD1L, a mitochondrial glycerol-3-phosphate dehydrogenase protein essential for glycerolipid metabolism and energy production. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples and is validated for Western blot applications. By targeting the GPD1L protein, researchers can accurately detect and analyze its expression in various cell types, making it invaluable for studies in metabolism, energy regulation, and mitochondrial function.
GPD1L plays a crucial role in maintaining cellular energy balance and lipid metabolism, making it a key player in metabolic diseases such as obesity, diabetes, and cardiovascular disorders. Understanding the function and regulation of GPD1L is essential for developing targeted therapies that can modulate its activity and potentially treat metabolic disorders effectively. This antibody enables researchers to delve deeper into the intricate mechanisms involving GPD1L, offering insights that can lead to novel therapeutic interventions in metabolic diseases.
Product Name: | GPD1L Antibody |
Product Sku: | CPAB0236 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human GPD1L mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GPD1L amino acids 1-351 purified from Ecoli. |
Clone: | PAT14E2AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA, Flow Cytometry |
Purification Method: | GPD1L antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG1 |
Background: | Glycerol-3-phosphate dehydrogenase 1-like protein (GPD1L) converts sn-glycerol 3-phosphate to glycerone phosphate. GPD1L is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Mutations in the GPD1L gene are the cause of SIDS (sudden infant death syndrome) and Brugada syndrome type 2 (an autosomal dominant tachyarrhythmia). |
Synonyms: | Glycerol-3-phosphate dehydrogenase 1-like protein, GPD1-L, GPD1L, KIAA0089. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |