Anti-GPCR / LGR6 Antibody (CAB9128)
- SKU:
- CAB9128
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Metabolism
Description
Anti-GPCR / LGR6 Antibody (CAB9128)
The GPCR LGR6 Rabbit Monoclonal Antibody (CAB9128) is a cutting-edge research tool for scientists studying G protein-coupled receptors (GPCRs) and the LGR6 protein. As a key regulator of stem cell function and tissue regeneration, LGR6 is essential for understanding processes such as wound healing and organ development.This antibody, meticulously produced in rabbits, is highly specific and sensitive for detecting LGR6 in various experimental settings, including immunofluorescence and flow cytometry. Its exceptional performance in applications such as Western blotting and immunohistochemistry makes it an indispensable tool for researchers investigating the role of LGR6 in stem cell biology, cancer biology, and tissue maintenance.
By targeting the GPCR LGR6, researchers can unravel the complex signaling pathways and molecular mechanisms underlying cellular processes, paving the way for innovative therapeutic strategies in regenerative medicine and cancer treatment. The GPCR LGR6 Rabbit Monoclonal Antibody (CAB9128) is a valuable asset in unlocking the potential of LGR6 as a novel therapeutic target in diverse fields of biomedical research.
| Antibody Name: | Anti-GPCR / LGR6 Antibody |
| Antibody SKU: | CAB9128 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human GPCR / LGR6 |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: | HeLa, MCF7, Rat testis |
| Immunogen: | A synthesized peptide derived from human GPCR / LGR6 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 59352 |
| Uniprot: | Q9HBX8 |
| Cellular Location: | |
| Calculated MW: | 104kDa |
| Observed MW: | 104KDa |
| Synonyms: | GPCR, VTS20631 |
| Background: | This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | LGR6: a leucine-rich repeat-containing G-protein-coupled receptor. Receptor for R-spondins, potent stimulators of adult stem cell proliferation. A marker of adult stem cells. A Wnt receptor component that enhances Wnt signaling by soluble R-spondin proteins. A marker of a multipotent population of skin stem cells. Three isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Tumor suppressor; Membrane protein, integral Chromosomal Location of Human Ortholog: 1q32.1 Cellular Component: integral to plasma membrane; plasma membrane; trans-Golgi network membrane; vesicle Molecular Function:G-protein coupled receptor activity; protein binding; transmembrane receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of cell migration; positive regulation of Wnt receptor signaling pathway; Wnt receptor signaling pathway |
| NCBI Summary: | This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9HBX8 |
| NCBI GenInfo Identifier: | 158519993 |
| NCBI Gene ID: | 59352 |
| NCBI Accession: | Q9HBX8.3 |
| UniProt Secondary Accession: | Q9HBX8,Q5T509, Q5T512, Q6UY15, Q86VU0, Q96K69, Q9BYD7 |
| UniProt Related Accession: | Q9HBX8 |
| Molecular Weight: | 99,295 Da |
| NCBI Full Name: | Leucine-rich repeat-containing G-protein coupled receptor 6 |
| NCBI Synonym Full Names: | leucine-rich repeat containing G protein-coupled receptor 6 |
| NCBI Official Symbol: | LGR6Â Â |
| NCBI Official Synonym Symbols: | GPCR; VTS20631Â Â |
| NCBI Protein Information: | leucine-rich repeat-containing G-protein coupled receptor 6 |
| UniProt Protein Name: | Leucine-rich repeat-containing G-protein coupled receptor 6 |
| Protein Family: | Leucine-rich repeat-containing G-protein coupled receptor |
| UniProt Gene Name: | LGR6Â Â |
| UniProt Entry Name: | LGR6_HUMAN |
 | Western blot - GPCR / LGR6 Rabbit mAb (CAB9128) |
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