Glypican 3 (GPC3) Rabbit Monoclonal Antibody (CAB11686)
- SKU:
- CAB11686
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | Glypican 3 (GPC3) Rabbit Monoclonal Antibody |
SKU: | CAB11686 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-211 of human Glypican 3 (GPC3) (P51654). |
Sequence: | PGQA QPPP PPPD ATCH QVRS FFQR LQPG LKWV PETP VPGS DLQV CLPK GPTC CSRK MEEK YQLT ARLN MEQL LQSA SMEL KFLI IQNA AVFQ EAFE IVVR HAKN YTNA MFKN NYPS LTPQ AFEF VGEF FTDV SLYI LGSD INVD DMVN ELFD SLFP VIYT QLMN PGLP DSAL DINE CLRG ARRD LKVF GNF |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; Glypican 3 (GPC3) |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Extracellular side, GPI-anchor, Lipid-anchor, Secreted, extracellular space. |
Calculated MW: | 66kDa |
Observed MW: | 70kDa |
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2719 |
Clone Number: | ARC0675 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |