Glypican 3 (GPC3) Rabbit Polyclonal Antibody (CAB12383)
- SKU:
- CAB12383
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | Glypican 3 (GPC3) Rabbit Polyclonal Antibody |
SKU: | CAB12383 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 290-550 of human Glypican 3 (Glypican 3 (GPC3)) (NP_004475.1). |
Sequence: | VEID KYWR EYIL SLEE LVNG MYRI YDME NVLL GLFS TIHD SIQY VQKN AGKL TTTI GKLC AHSQ QRQY RSAY YPED LFID KKVL KVAH VEHE ETLS SRRR ELIQ KLKS FISF YSAL PGYI CSHS PVAE NDTL CWNG QELV ERYS QKAA RNGM KNQF NLHE LKMK GPEP VVSQ IIDK LKHI NQLL RTMS MPKG RVLD KNLD EEGF ESGD CGDD EDEC IGGS GDGM IKVK NQLR FLAE LAYD LDVD DAPG NSQQ ATPK DNEI S |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; Glypican 3 (GPC3) |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Extracellular side, GPI-anchor, Lipid-anchor, Secreted, extracellular space. |
Calculated MW: | 66kDa |
Observed MW: | 70kDa |
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2719 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |