The GPC1 Polyclonal Antibody (CAB13019) is a valuable tool for researchers studying GPC1, a protein involved in cell signaling and tumorigenesis. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the GPC1 protein, researchers can detect and analyze its expression in various cell types, making it ideal for investigations in cancer biology and cell signaling pathways.GPC1, a member of the glypican family of heparan sulfate proteoglycans, is known to play a role in promoting tumor growth and metastasis through its involvement in signaling pathways that regulate cell proliferation and migration.
By studying GPC1 expression and function, researchers can gain insights into its potential as a therapeutic target for cancer treatment. Understanding the molecular mechanisms underlying GPC1 activity is essential for developing targeted therapies that can effectively inhibit tumor progression and metastasis.
Product Name:
GPC1 Rabbit Polyclonal Antibody
SKU:
CAB13019
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 290-420 of human GPC1 (NP_002072.2).
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
Purification Method:
Affinity purification
Gene ID:
2817
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GPC1 Rabbit pAb (CAB13019) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
