UniProt Protein Function: | GPBP1: a novel vascular protein differentially expressed in human atherogenesis. Can be found in the plasma, thus it may be a possible marker for atherosclerosis.Protein type: Transcription factorChromosomal Location of Human Ortholog: 5q11.2Cellular Component: intracellular membrane-bound organelle; cytoplasm; nucleolus; plasma membraneMolecular Function: DNA binding; transcription factor activityBiological Process: transcription, DNA-dependent; positive regulation of transcription, DNA-dependent |
UniProt Protein Details: | |
NCBI Summary: | This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011] |
UniProt Code: | Q86WP2 |
NCBI GenInfo Identifier: | 291327500 |
NCBI Gene ID: | 65056 |
NCBI Accession: | NP_001120707.2 |
UniProt Secondary Accession: | Q86WP2,Q6NSH6, Q9H0D4, Q9H785, Q9NSN4, A6NKW3 |
UniProt Related Accession: | Q86WP2 |
Molecular Weight: | 33,830 Da |
NCBI Full Name: | vasculin isoform 3 |
NCBI Synonym Full Names: | GC-rich promoter binding protein 1 |
NCBI Official Symbol: | GPBP1Â Â |
NCBI Official Synonym Symbols: | GPBP; SSH6; VASCULINÂ Â |
NCBI Protein Information: | vasculin |
UniProt Protein Name: | Vasculin |
UniProt Synonym Protein Names: | GC-rich promoter-binding protein 1; Vascular wall-linked protein |
Protein Family: | Vasculin |
UniProt Gene Name: | GPBP1Â Â |
UniProt Entry Name: | GPBP1_HUMAN |