GP6 Rabbit Polyclonal Antibody (CAB14999)
- SKU:
- CAB14999
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | GP6 Rabbit Polyclonal Antibody |
SKU: | CAB14999 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 21-267 of human GP6 (NP_057447.5). |
Sequence: | QSGP LPKP SLQA LPSS LVPL EKPV TLRC QGPP GVDL YRLE KLSS SRYQ DQAV LFIP AMKR SLAG RYRC SYQN GSLW SLPS DQLE LVAT GVFA KPSL SAQP GPAV SSGG DVTL QCQT RYGF DQFA LYKE GDPA PYKN PERW YRAS FPII TVTA AHSG TYRC YSFS SRDP YLWS APSD PLEL VVTG TSVT PSRL PTEP PSPV AEFS EATA ELTV SFTN EVFT TETS RSIT ASPK ESDS PAGP ARQY YTK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | GPIV; GPVI; BDPLT11; GP6 |
Positive Sample: | K-562,HEL,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass membrane protein. |
Calculated MW: | 37kDa |
Observed MW: | 37kDa |
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 51206 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |