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GP5 Antibody (PACO02249)

SKU:
PACO02249
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€319
Frequently bought together:

Description

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GP5 Antibody (PACO02249)

The GP5 Monoclonal Antibody (PACO02249) offered by AssayGenie is a highly specific and reliable tool for research involving the GP5 protein. This antibody is produced by hybridoma technology and is suitable for a variety of applications, including ELISA, Western blot, and immunohistochemistry.The GP5 protein is known for its involvement in virus-host cell interactions, particularly in the context of viral entry and replication. By targeting the GP5 protein, researchers can gain insights into the mechanisms underlying viral infections and potentially identify new therapeutic targets for combating viral diseases.

With its high specificity and sensitivity, the GP5 Monoclonal Antibody (PACO02249) is an invaluable resource for studies in virology, immunology, and infectious diseases. By using this antibody, researchers can advance our understanding of viral pathogenesis and contribute to the development of novel antiviral strategies.

Antibody Name:GP5 Antibody
Antibody SKU:PACO02249
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:WB:1:500-1:2000
Species Reactivity:Human, Mouse, Rat
Immunogen:synthesized peptide derived from the Internal region of human CD42d.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:GP5; Platelet glycoprotein V; GPV; Glycoprotein 5; CD42d
UniProt Protein Function:GPV: The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.
UniProt Protein Details:

Protein type:Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function:collagen binding; protein binding

Biological Process: axonogenesis; blood coagulation; blood coagulation, intrinsic pathway; cell adhesion; cell-matrix adhesion; platelet activation

NCBI Summary:Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010]
UniProt Code:P40197
NCBI GenInfo Identifier:4758460
NCBI Gene ID:2814
NCBI Accession:NP_004479.1
UniProt Secondary Accession:P40197,D1MER9,
UniProt Related Accession:P40197
Molecular Weight:60,959 Da
NCBI Full Name:platelet glycoprotein V
NCBI Synonym Full Names:glycoprotein V platelet
NCBI Official Symbol:GP5  
NCBI Official Synonym Symbols:GPV; CD42d  
NCBI Protein Information:platelet glycoprotein V
UniProt Protein Name:Platelet glycoprotein V
UniProt Synonym Protein Names:Glycoprotein 5; CD_antigen: CD42d
Protein Family:Protein
UniProt Gene Name:GP5  
UniProt Entry Name:GPV_HUMAN

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