The GP2 Polyclonal Antibody (CAB12438) is specifically designed for research related to GP2, a glycoprotein found in the membranes of pancreatic zymogen granules. This antibody, produced through rabbit immunization, is highly specific and reactive with human samples, making it a valuable tool for studies focusing on pancreatitis, pancreatic cancer, and other pancreatic disorders.GP2 plays a vital role in the exocytosis of pancreatic digestive enzymes and has been implicated in the pathogenesis of various pancreatic diseases. The GP2 Polyclonal Antibody binds specifically to the GP2 protein, allowing for its detection and analysis in different cell types.
Its application in Western blotting and other techniques makes it ideal for investigations into the molecular mechanisms underlying pancreatic diseases.Understanding the function and regulation of GP2 is essential for developing targeted therapies for pancreatic disorders. The GP2 Polyclonal Antibody provides researchers with a reliable tool for studying the role of GP2 in health and disease, ultimately paving the way for new advances in the field of pancreatic research.
Product Name:
GP2 Rabbit Polyclonal Antibody
SKU:
CAB12438
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 111-387 of human GP2 (NP_001007243.2).
This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2813
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GP2 antibody (CAB12438) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
