The GP Antibody (PAC050246) is a polyclonal antibody specifically designed for research involving GP, a protein that plays a crucial role in various physiological processes. This antibody, produced in rabbits, is highly reactive with samples from various species and has been validated for use in Western blot applications. By binding to the GP protein, this antibody enables the detection and analysis of GP in different cell types, making it an essential tool for studies in virology, immunology, and infectious diseases.
GP, also known as glycoprotein, is a key component of certain viruses, including Ebola and Marburg viruses, where it facilitates viral entry into host cells and modulates immune responses. Research on GP is vital for understanding viral pathogenesis, developing antiviral therapies, and designing vaccines against deadly viral infections. The GP Antibody is a valuable resource for scientists and researchers working to unravel the complexities of viral infections and combat emerging infectious diseases.
Antibody Name:
GP Antibody (PACO50246)
Antibody SKU:
PACO50246
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Zaire ebolavirus
Immunogen:
Recombinant Zaire ebolavirus Pre-small/secreted glycoprotein protein (33-364AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: GP antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. predicted band size: 42 kDa. observed band size: 42 kDa..
Background:
sGP seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. Does not seem to be involved in activation of primary macrophages. Does not seem to interact specifically with neutrophils (By similarity).
Synonyms:
Pre-small/secreted glycoprotein (pre-sGP) [Cleaved into: Small/secreted glycoprotein (sGP); Delta-peptide], GP
UniProt Protein Function:
sGP seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. Does not seem to be involved in activation of primary macrophages. Does not seem to interact specifically with neutrophils ().
