GOSR1 Antibody (PACO65153)
- SKU:
- PACO65153
- Product Type:
- Antibody
- Reactivity:
- Human, Mouse
- Clonality:
- Polyclonal
- Target:
- GOSR1
Description
GOSR1 Antibody (PACO65153)
The GOSR1 Polyclonal Antibody (PACO65153) is a valuable tool for research involving GOSR1, a critical protein involved in vesicle trafficking and membrane fusion processes within cells. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in a variety of applications, including Western blot and immunofluorescence.GOSR1, also known as Golgi SNAP receptor complex member 1, plays a crucial role in maintaining the structure and function of the Golgi apparatus, a key organelle responsible for processing and sorting proteins within the cell. Dysregulation of GOSR1 has been linked to various diseases, including neurodegenerative disorders and cancer, highlighting its importance in cellular processes.
By utilizing the GOSR1 Polyclonal Antibody, researchers can study the expression and localization of GOSR1 in different cell types and tissues, providing valuable insights into its function and potential implications in disease pathology. This antibody is a valuable tool for investigations in cell biology, neuroscience, and cancer research, offering researchers the ability to further understand the roles of GOSR1 in health and disease.
| Product Name: | GOSR1 Antibody | ||||||
| SKU: | PACO65153 | ||||||
| Size: | 50μl, 100μl | ||||||
| UniProt No: | O95249 | ||||||
| Target Names: | GOSR1 | ||||||
| Alternative Names: | GOSR1; GS28; Golgi SNAP receptor complex member 1; 28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; GOS-28 | ||||||
| Species Reactivity: | Human, Mouse | ||||||
| Immunogen: | Recombinant Human Golgi SNAP receptor complex member 1 protein (1-115AA) | ||||||
| Immunogen Species: | Homo sapiens (Human) | ||||||
| Clonality: | Polyclonal | ||||||
| Purification Method: | Antigen Affinity Purified | ||||||
| Conjugate: | Non-conjugated | ||||||
| Form: | Liquid | ||||||
| Storage: | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
| Lead Time: | Basically, we can dispatch the products out in 7-10 working days after receiving your orders. Delivery time may differ depending on the purchasing method or location. Please consult your local distributors for specific delivery times. | ||||||
| Tested Applications: | ELISA WB IHC | ||||||
| Recommended Dilution: |
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| Function: | Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi. |
| Gene References into Functions: |
|
| Subcellular Location: | Golgi apparatus membrane; Single-pass type IV membrane protein. |
| Protein Families: | GOSR1 family |
| Database Links: | HGNC: 4430 OMIM: 604026 KEGG: hsa:9527 STRING: 9606.ENSP00000225724 UniGene: Hs.462680 |
 | Western blot All lanes: GOSR1 antibody at 16μg/ml + Mouse liver tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 29, 22 kDa Observed band size: 29 kDa |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO65153 at dilution of 1:100 |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO65153 at dilution of 1:100. |
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