The GORASP1 Polyclonal Antibody (CAB6609) is a valuable tool for researchers studying GORASP1, a protein involved in maintaining the structure of the Golgi apparatus. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to GORASP1, this antibody allows for the detection and analysis of this protein in various cell types, making it an essential tool for studies in cell biology and molecular biology.GORASP1 is a critical player in Golgi structure and function, influencing processes such as protein trafficking and secretion.
Dysregulation of GORASP1 has been linked to various diseases, including neurodegenerative disorders and cancer. By studying the role of GORASP1, researchers can gain insights into these diseases and potentially identify new therapeutic targets. The GORASP1 Polyclonal Antibody is a valuable resource for researchers looking to further understand the function of GORASP1 and its implications in human health and disease.
Product Name:
GRASP65 Rabbit Polyclonal Antibody
SKU:
CAB6609
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 221-440 of human GRASP65 (NP_114105.1).
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Alternative splicing results in multiple transcript variants of this gene.
Purification Method:
Affinity purification
Gene ID:
64689
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GRASP65 antibody (CAB6609) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
