The GORAB Polyclonal Antibody (CAB17245) is a valuable tool for researchers studying GORAB, a protein involved in Golgi organization and regulation. This antibody, produced in rabbits, has high specificity for human samples and is validated for use in Western blot applications. By binding to the GORAB protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential reagent for investigations in cell biology and molecular biology.GORAB plays a crucial role in maintaining the structure and function of the Golgi apparatus, a key organelle involved in protein processing and secretion.
Dysregulation of GORAB activity has been linked to various diseases, including skeletal disorders and skin abnormalities. Understanding the function and regulation of GORAB is essential for unraveling its role in these conditions and developing potential therapeutic interventions.Overall, the GORAB Polyclonal Antibody is a reliable tool for researchers interested in exploring the role of GORAB in cellular processes and disease pathology. Its high specificity and versatility make it an indispensable component for studies aimed at unraveling the molecular mechanisms underlying Golgi organization and dysfunction.
Product Name:
GORAB Rabbit Polyclonal Antibody
SKU:
CAB17245
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GORAB (NP_001139511.1).
This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
92344
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GORAB Rabbit pAb (CAB17245) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
