The GOLPH3L Monoclonal Antibody (PAC027113) is a essential tool for researchers studying GOLPH3L, a golgi phosphoprotein involved in intracellular trafficking and protein glycosylation processes. This monoclonal antibody, generated in mice, exhibits high specificity for human samples and is validated for use in various applications including Western blot and immunofluorescence.GOLPH3L, also known as Golgi phosphoprotein 3-like, is a key player in maintaining Golgi structure and function, as well as in regulating protein trafficking between the Golgi apparatus and cell membrane. It is implicated in various cellular processes such as cell proliferation, migration, and invasion, making it a promising target for research in cancer biology and neurodegenerative diseases.
By using the GOLPH3L Monoclonal Antibody, researchers can effectively detect and analyze GOLPH3L protein expression in different cell types, providing valuable insights into its role in cellular function and disease progression. This antibody is an invaluable asset for studies aiming to unravel the molecular mechanisms underlying Golgi-related pathways and their impact on physiological and pathological conditions.
Antibody Name:
GOLPH3L Antibody (PACO27113)
Antibody SKU:
PACO27113
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Golgi phosphoprotein 3-like protein (6-285AA)
Immunohistochemistry of paraffin-embedded human colon cancer using PACO27113 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human melanoma using PACO27113 at dilution of 1:100.
Background:
Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane.
GOLPH3L: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking. [provided by RefSeq, Jul 2008]Protein type: Unknown functionChromosomal Location of Human Ortholog: 1q21.3Cellular Component: Golgi membrane; trans-Golgi network membraneMolecular Function: protein bindingBiological Process: Golgi organization and biogenesis; positive regulation of protein secretion
UniProt Protein Details:
NCBI Summary:
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking. [provided by RefSeq, Jul 2008]
