The Golga4 Polyclonal Antibody (CAB10216) is a valuable tool for researchers studying Golga4, a protein involved in regulating cellular transport and Golgi organization. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the Golga4 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and molecular biology.Golga4 is an essential protein in maintaining the structure and function of the Golgi apparatus, a key organelle involved in protein processing and sorting within the cell.
Dysregulation of Golga4 has been linked to disruptions in cellular transport pathways and is associated with certain genetic disorders and neurodegenerative diseases. Research on Golga4 is vital for advancing our understanding of cellular dynamics and disease mechanisms, with potential implications for developing targeted therapies in the future.
Product Name:
GOLGA4 Rabbit Polyclonal Antibody
SKU:
CAB10216
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GOLGA4 (NP_002069.2).
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein has been postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Purification Method:
Affinity purification
Gene ID:
2803
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GOLGA4 antibody (CAB10216) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
