The Golga2 Polyclonal Antibody (CAB16248) is a valuable tool for researchers studying the Golgi apparatus protein Golga2. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the Golga2 protein, this antibody enables researchers to detect and analyze Golga2 in various cell types, making it ideal for investigations in cell biology and organelle function.Golga2, also known as GM130, is a key protein involved in maintaining Golgi structure and function. It plays a critical role in vesicle transport, protein sorting, and post-translational modifications within the Golgi apparatus.
Dysregulation of Golga2 has been linked to various diseases, including neurodegenerative disorders and cancer. By studying Golga2 with this antibody, researchers can gain valuable insights into Golgi dynamics and its impact on cellular processes.Overall, the Golga2 Polyclonal Antibody (CAB16248) is a reliable tool for investigating the role of Golga2 in cellular function and disease pathology. Its specificity and sensitivity make it a valuable asset for researchers seeking to unravel the complexities of Golgi biology.
Product Name:
GM130 Rabbit Polyclonal Antibody
SKU:
CAB16248
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human GM130 (NP_004477.3).
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined.
Purification Method:
Affinity purification
Gene ID:
2801
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GM130 Rabbit pAb (CAB16248) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
