GNS Rabbit Polyclonal Antibody (CAB7489)
- SKU:
- CAB7489
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GNS Rabbit Polyclonal Antibody |
SKU: | CAB7489 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 293-552 of human GNS (NP_002067.1). |
Sequence: | WQTL LSVD DLVE KLVK RLEF TGEL NNTY IFYT SDNG YHTG QFSL PIDK RQLY EFDI KVPL LVRG PGIK PNQT SKML VANI DLGP TILD IAGY DLNK TQMD GMSL LPIL RGAS NLTW RSDV LVEY QGEG RNVT DPTC PSLS PGVS QCFP DCVC EDAY NNTY ACVR TMSA LWNL QYCE FDDQ EVFV EVYN LTAD PDQI TNIA KTID PELL GKMN YRLM MLQS CSGP TCRT PGVF DPGY RFDP RLMF SNRG SVRT RRFS KHLL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | G6S; GNS |
Positive Sample: | BT-474,NCI-H460,293T,SKOV3,HeLa,Mouse liver,Mouse kidney,Mouse spleen,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome. |
Calculated MW: | 62kDa |
Observed MW: | 62kDa |
The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
Purification Method: | Affinity purification |
Gene ID: | 2799 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |