The GNPTAB Polyclonal Antibody (CAB13717) is a valuable tool for researchers studying GNPTAB, a gene involved in the regulation of lysosomal enzyme targeting. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for Western blot applications. By binding to the GNPTAB protein, this antibody allows for the detection and analysis of GNPTAB in various cell types, making it ideal for studies in lysosomal biology and enzyme targeting mechanisms.GNPTAB plays a crucial role in lysosomal enzyme targeting and is essential for the proper functioning of lysosomes in the cell.
Dysregulation of GNPTAB has been linked to lysosomal storage disorders and other lysosomal-related diseases. Therefore, understanding the function and regulation of GNPTAB can provide insights into potential therapeutic targets for these disorders.Overall, the GNPTAB Polyclonal Antibody is a valuable tool for researchers investigating lysosomal biology, enzyme targeting mechanisms, and lysosomal-related diseases. Its high reactivity and specificity make it a reliable choice for studying the role of GNPTAB in cellular processes and disease mechanisms.
Product Name:
GNPDA1 Rabbit Polyclonal Antibody
SKU:
CAB13717
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human GNPDA1 (NP_005462.1).
Glucosamine-6-phosphate deaminase (EC 3.5.99.6) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium (Arreola et al., 2003 [PubMed 12965206]).
Purification Method:
Affinity purification
Gene ID:
10007
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GNPDA1 Rabbit pAb (CAB13717) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
