The GNG2 Polyclonal Antibody (CAB10309) is a valuable tool for researchers studying GNG2, a protein involved in various cellular processes, including signal transduction and cell proliferation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the GNG2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in areas such as neuroscience and cancer research.GNG2, a member of the G protein family, plays a crucial role in signal transduction pathways, influencing diverse cellular functions such as cell growth, differentiation, and migration.
Its involvement in these processes underscores its importance in physiological and pathological conditions, making it a promising target for therapeutic interventions. Further exploration of GNG2's functions is essential for advancing our understanding of its role in disease development and progression, paving the way for potential therapeutic strategies targeting this protein.
Product Name:
GNG2 Rabbit Polyclonal Antibody
SKU:
CAB10309
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-71 of human GNG2 (NP_444292.1).
Sequence:
MASN NTAS IAQA RKLV EQLK MEAN IDRI KVSK AAAD LMAY CEAH AKED PLLT PVPA SENP FREK KFFC AIL
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:1000 - 1:2000
Synonyms:
HG3F1; GNG2
Positive Sample:
A-431,Mouse lung,Rat lung
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, Cytoplasmic side, Lipid-anchor.
Calculated MW:
8kDa
Observed MW:
8kDa
This gene encodes one of the gamma subunits of a guanine nucleotide-binding protein. Such proteins are involved in signaling mechanisms across membranes. Various subunits forms heterodimers which then interact with the different signal molecules.
Purification Method:
Affinity purification
Gene ID:
54331
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GNG2 antibody (CAB10309) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
