The GNB5 Polyclonal Antibody (CAB4447) is a valuable tool for researchers studying GNB5, a guanine nucleotide-binding protein involved in signal transduction and cellular communication. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the GNB5 protein, allowing for accurate detection and analysis in a variety of cell types.GNB5 plays a crucial role in many cellular processes, including receptor signaling, intracellular trafficking, and cytoskeletal dynamics. Its involvement in these pathways makes it a key target for research in fields such as cell biology, neurobiology, and cancer biology.
By understanding the function and regulation of GNB5, researchers can gain valuable insights into disease mechanisms and potential therapeutic strategies.Overall, the GNB5 Polyclonal Antibody (CAB4447) is a reliable tool for investigating the role of GNB5 in various biological processes and disease states. Its high specificity and sensitivity make it an essential component of any research program focused on understanding the intricate mechanisms of cellular signaling and communication.
Product Name:
GNB5 Rabbit Polyclonal Antibody
SKU:
CAB4447
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GNB5 (NP_006569.1).
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist.
Purification Method:
Affinity purification
Gene ID:
10681
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GNB5 antibody (CAB4447) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 60s.
