The GNB2 Polyclonal Antibody (CAB8422) is a valuable tool for researchers studying GNB2, a crucial protein involved in signal transduction pathways. This antibody is raised in rabbits and is highly specific to human samples, making it ideal for Western blot applications. By binding to GNB2, this antibody enables accurate detection and analysis of GNB2 protein levels in various cell types.GNB2 is a key player in intracellular signal transduction, particularly in processes involving G protein-coupled receptors. Dysregulation of GNB2 signaling has been linked to various diseases, including cancer, cardiovascular disorders, and neurological conditions.
Therefore, studying the expression and function of GNB2 is essential for understanding its role in disease pathogenesis and potentially identifying therapeutic targets.With its high reactivity and specificity, the GNB2 Polyclonal Antibody (CAB8422) is a valuable asset for researchers investigating the function of GNB2 in different physiological and pathological contexts. Its use in Western blotting allows for precise quantification and characterization of GNB2 protein levels, providing insights that can contribute to advancements in the fields of molecular biology, pharmacology, and drug development.
Product Name:
GNB2 Rabbit Polyclonal Antibody
SKU:
CAB8422
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human GNB2 (NP_005264.2).
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR.
Purification Method:
Affinity purification
Gene ID:
2783
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GNB2 Rabbit pAb (CAB8422) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
