The GNB1L Polyclonal Antibody (CAB7810) is a vital tool for researchers studying GNB1L, a key protein involved in signaling pathways and cellular processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for various research applications such as Western blotting. By binding to the GNB1L protein, this antibody allows for the detection and analysis of GNB1L in different cell types, offering valuable insights into its functions and roles in biological processes.GNB1L, also known as G protein beta subunit-like, is known for its involvement in multiple signaling cascades and pathways that regulate various cellular activities, including cell growth, differentiation, and proliferation.
Understanding the functions and mechanisms of GNB1L is essential for gaining insights into its potential implications in diseases such as cancer, neurological disorders, and metabolic conditions. The GNB1L Polyclonal Antibody provides researchers with a valuable tool to explore the roles of GNB1L in health and disease, paving the way for innovative therapeutic strategies and interventions.
Product Name:
GNB1L Rabbit Polyclonal Antibody
SKU:
CAB7810
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-327 of human GNB1L (NP_443730.1).
This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders. Transcripts from this gene share exons with some transcripts from the C22orf29 gene.
Purification Method:
Affinity purification
Gene ID:
54584
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GNB1L antibody (CAB7810) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
