The GNB1 Polyclonal Antibody (CAB1867) is a valuable tool for research involving GNB1, a key protein involved in intracellular signaling pathways. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the GNB1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and drug development.GNB1, also known as guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, plays a critical role in transducing signals from G protein-coupled receptors to downstream effectors, thereby regulating various cellular processes.
Its involvement in diverse signaling cascades makes it a promising target for research in areas such as neuroscience, cardiovascular biology, and cancer. Understanding the function of GNB1 is essential for uncovering new therapeutic strategies that target these signaling pathways for disease treatment.
Product Name:
GNB1 Rabbit Polyclonal Antibody
SKU:
CAB1867
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human GNB1 (NP_002065.1).
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2782
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GNB1 antibody (CAB1867) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
