The GNAT2 Polyclonal Antibody (CAB10352) is a crucial tool for research involving GNAT2, a G protein-coupled receptor involved in visual signal transduction. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the GNAT2 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for studies in vision research and sensory biology.
GNAT2 plays a crucial role in the phototransduction cascade, where it helps convert light signals into electrical signals in the retina. Understanding the function of GNAT2 is essential for unraveling the mechanisms behind vision and visual disorders. This antibody provides researchers with a powerful tool to investigate the role of GNAT2 in vision, ultimately leading to advancements in the treatment of vision-related diseases and conditions.
Product Name:
GNAT2 Rabbit Polyclonal Antibody
SKU:
CAB10352
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human GNAT2 (NP_005263.1).
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones.
Purification Method:
Affinity purification
Gene ID:
2780
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of HepG2 cells, using GNAT2 antibody (CAB10352) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
