The GNAQ Polyclonal Antibody (CAB14736) is a valuable tool for researchers studying GNAQ, a key protein involved in various cellular processes, including intracellular signaling pathways and cellular proliferation. This antibody, produced in rabbits, displays high specificity for GNAQ in human samples and is validated for use in Western blot applications. By binding to the GNAQ protein, this antibody enables accurate detection and analysis, making it an essential reagent for studies in cell biology, cancer research, and molecular signaling pathways.GNAQ is a guanine nucleotide-binding protein that plays a crucial role in mediating signals from cell surface receptors to intracellular effectors, thereby regulating important cellular functions.
Dysregulation of GNAQ signaling has been implicated in various diseases, including cancer, cardiovascular disorders, and neurological conditions. Understanding the mechanisms underlying GNAQ activity is essential for developing targeted therapies that modulate these pathways for therapeutic purposes.Overall, the GNAQ Polyclonal Antibody (CAB14736) is a valuable tool for researchers investigating the role of GNAQ in normal cellular physiology and disease processes. Its high specificity and versatility make it an indispensable reagent for a wide range of research applications in molecular and cellular biology.
Product Name:
GNAQ Rabbit Polyclonal Antibody
SKU:
CAB14736
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human GNAQ (NP_002063.2).
This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.
Purification Method:
Affinity purification
Gene ID:
2776
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GNAQ antibody (CAB14736) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
