The GNAI3 Polyclonal Antibody (CAB1922) is designed for research involving GNAI3, a protein involved in various physiological processes, including signal transduction and cell growth regulation. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blotting and immunohistochemistry applications.GNAI3 is a member of the G protein family and plays a crucial role in mediating the effects of various neurotransmitters and hormones on cellular signaling pathways.
Dysregulation of GNAI3 has been associated with a variety of diseases, including cancer, cardiovascular disorders, and neurological conditions.By detecting and analyzing GNAI3 protein levels in different cell types and tissues, researchers can gain insights into its function and potential involvement in disease development. This antibody is a valuable tool for studying the role of GNAI3 in cellular signaling pathways and its potential as a therapeutic target in various diseases.
Product Name:
GNAI3 Rabbit Polyclonal Antibody
SKU:
CAB1922
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GNAI3 (NP_006487.1).
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.
Purification Method:
Affinity purification
Gene ID:
2773
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GNAI3 Rabbit pAb (CAB1922) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 30s.
