The GNAI3 Polyclonal Antibody (CAB15674) is a valuable tool for researchers studying GNAI3, a signaling protein involved in various cellular processes. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it suitable for use in Western blot and immunohistochemistry applications. By binding to the GNAI3 protein, this antibody enables the detection and analysis of GNAI3 levels in different cell types and tissues, making it ideal for studies in signal transduction pathways and molecular biology.GNAI3 is a member of the G protein family that plays a crucial role in mediating intracellular signaling cascades in response to extracellular stimuli.
Its involvement in diverse physiological processes, such as cell growth, differentiation, and chemotaxis, highlights its importance as a target for research in various fields, including cancer biology and pharmacology. Understanding the function and regulation of GNAI3 is essential for uncovering novel therapeutic targets and developing treatments for diseases associated with dysregulated signaling pathways.
Product Name:
GNAI3 Rabbit Polyclonal Antibody
SKU:
CAB15674
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GNAI3 (NP_006487.1).
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.
Purification Method:
Affinity purification
Gene ID:
2773
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GNAI3 antibody (CAB15674) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
