The GNAI3 Polyclonal Antibody (CAB13307) is a valuable tool for researchers studying GNAI3, a key protein involved in signal transduction pathways. This antibody, produced in rabbits, demonstrates high specificity and sensitivity towards human samples, making it a reliable tool for Western blot applications. By binding specifically to GNAI3, this antibody enables the detection and analysis of the protein in various cell types, making it an essential component for studies in cell signaling and cancer research.GNAI3, a member of the G protein family, plays a crucial role in mediating intracellular signaling cascades triggered by various extracellular stimuli.
Its involvement in regulating cell proliferation, differentiation, and migration highlights its importance in cancer progression and metastasis. Furthermore, GNAI3 has been implicated in other diseases such as cardiovascular disorders, making it a promising target for therapeutic interventions.By utilizing the GNAI3 Polyclonal Antibody, researchers can gain valuable insights into the functions and mechanisms of GNAI3 in health and disease. Understanding the role of GNAI3 in signal transduction pathways may lead to the development of novel treatments for cancer and other related conditions.
Product Name:
[KO Validated] GNAI3 Rabbit Polyclonal Antibody
SKU:
CAB13307
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-354 of human GNAI3 (NP_006487.1).
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.
Purification Method:
Affinity purification
Gene ID:
2773
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] GNAI3 Rabbit pAb (CAB13307) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
