The GNAI2 Polyclonal Antibody (CAB14547) is a valuable tool for researchers studying GNAI2, a key protein involved in signal transduction pathways. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the GNAI2 protein, this antibody enables the detection and analysis of GNAI2 expression in various cell types, making it an essential component for investigations in signal transduction and cell signaling pathways.GNAI2, also known as G Protein Subunit Alpha I2, plays a crucial role in mediating intracellular signaling cascades that regulate various cellular processes, including cell proliferation, differentiation, and migration.
Dysregulation of GNAI2 has been implicated in numerous diseases, such as cancer, cardiovascular disorders, and neurological conditions. Therefore, understanding the function and regulation of GNAI2 is essential for elucidating the underlying mechanisms of these diseases and developing targeted therapies.Overall, the GNAI2 Polyclonal Antibody (CAB14547) serves as a valuable tool for researchers seeking to investigate the role of GNAI2 in both normal physiological processes and disease states, paving the way for further advancements in biomedical research and therapeutic development.
Product Name:
GNAI2 Rabbit Polyclonal Antibody
SKU:
CAB14547
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-355 of human GNAI2 (NP_002061.1).
The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2771
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GNAI2 Rabbit pAb (CAB14547) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
