The GNA15 Polyclonal Antibody (CAB16866) is a valuable tool for researchers studying GNA15, a G protein-coupled receptor involved in various cellular signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the GNA15 protein, this antibody enables accurate detection and analysis in a range of cell types, making it an essential component for studies in cell biology and signal transduction research.
GNA15, a member of the G protein alpha subunit family, regulates intracellular signaling cascades that mediate diverse physiological processes, including cell proliferation, differentiation, and survival. Dysregulation of GNA15 signaling has been implicated in various diseases, such as cancer, cardiovascular disorders, and neurological conditions. Investigating the role of GNA15 in these contexts is crucial for advancing our understanding of disease mechanisms and identifying potential therapeutic targets.
Product Name:
GNA15 Rabbit Polyclonal Antibody
SKU:
CAB16866
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 112-374 of human GNA15 (NP_002059.3).
Enables G protein-coupled receptor binding activity. Involved in positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex.
Purification Method:
Affinity purification
Gene ID:
2769
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GNA15 Rabbit pAb (CAB16866) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
