The GNA14 Polyclonal Antibody (CAB10405) is a valuable tool for researchers studying GNA14, a G protein subunit involved in various cellular signaling pathways. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GNA14 protein, this antibody enables precise detection and analysis in a variety of cell types, making it well-suited for investigations in signal transduction and molecular biology.GNA14 plays a key role in mediating intracellular signaling cascades, impacting processes such as cell proliferation, migration, and differentiation. Dysregulation of GNA14 has been implicated in various diseases, including cancer and neurological disorders, highlighting its importance as a potential therapeutic target.
By elucidating the functions of GNA14, researchers can gain valuable insights into the underlying mechanisms of disease pathology and potentially identify new treatment strategies.Overall, the GNA14 Polyclonal Antibody (CAB10405) offers a reliable tool for investigating the role of GNA14 in cellular signaling pathways and disease pathogenesis. Its specificity and sensitivity make it an essential component of research efforts aimed at advancing our understanding of G protein signaling and its implications for human health.
Product Name:
GNA14 Rabbit Polyclonal Antibody
SKU:
CAB10405
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-350 of human GNA14 (NP_004288.1).
This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.
Purification Method:
Affinity purification
Gene ID:
9630
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GNA14 antibody (CAB10405) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
